AustralieFrV1, Main, Exploration, bibRecord, 008C92

High-Throughput Genotyping of Salmonella enterica Serovar Typhi Allowing Geographical Assignment of Haplotypes and Pathotypes within an Urban District of Jakarta, Indonesia

Identifieur interne : 008C92 ( Main/Exploration ); précédent : 008C91; suivant : 008C93

High-Throughput Genotyping of Salmonella enterica Serovar Typhi Allowing Geographical Assignment of Haplotypes and Pathotypes within an Urban District of Jakarta, Indonesia

Auteurs : Stephen Baker [Royaume-Uni, Viêt Nam] ; Kathryn Holt [Royaume-Uni] ; Esther Van De Vosse [Pays-Bas] ; Philippe Roumagnac [France] ; Sally Whitehead [Royaume-Uni] ; Emma King [Royaume-Uni] ; Philip Ewels [Royaume-Uni] ; Andrew Keniry [Royaume-Uni] ; Francois-Xavier Weill [France] ; Diane Lightfoot [Australie] ; Jaap T. Van Dissel [Pays-Bas] ; Kenneth E. Sanderson [Canada] ; Jeremy Farrar [Viêt Nam] ; Mark Achtman [Irlande (pays)] ; Panagiotis Deloukas [Royaume-Uni] ; Gordon Dougan [Royaume-Uni]

Source :

Journal of clinical microbiology : (Print) [ 0095-1137 ] ; 2008.

RBID : Pascal:08-0251112

Descripteurs français

Pascal (Inist)
- Salmonella typhi, Criblage haut débit, Génotype, Typage, Haplotype, Pathotype, Indonésie, Microbiologie.
Wicri :
- geographic : Indonésie.

English descriptors

KwdEn :
- Genotype, Haplotype, High throughput screening, Indonesia, Microbiology, Pathotype, Salmonella typhi, Typing.

Abstract

High-throughput epidemiological typing systems that provide phylogenetic and genotypic information are beneficial for tracking bacterial pathogens in the field. The incidence of Salmonella enterica serovar Typhi infection in Indonesia is high and is associated with atypical phenotypic traits such as expression of the j and the z66 flagellum antigens. Utilizing a high-throughput genotyping platform to investigate known nucleotide polymorphisms dispersed around the genome, we determined the haplotypes of 140 serovar Typhi isolates associated with Indonesia. We identified nine distinct serovar Typhi haplotypes circulating in Indonesia for more than 30 years, with eight of these present in a single Jakarta suburb within a 2-year period. One dominant haplotype, H59, is associated with j and z66 flagellum expression, representing a potential pathotype unique to Indonesia. Phylogenetic analysis suggests that H59 z66⁺,j⁺ isolates emerged relatively recently in terms of the origin of serovar Typhi and are geographically restricted. These data demonstrate the potential of high-throughput genotyping platforms for analyzing serovar Typhi populations in the field. The study also provides insight into the evolution of serovar Typhi and demonstrates the value of a molecular epidemiological technique that is exchangeable, that is internet friendly, and that has global utility.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395080

Affiliations:

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">High-Throughput Genotyping of Salmonella enterica Serovar Typhi Allowing Geographical Assignment of Haplotypes and Pathotypes within an Urban District of Jakarta, Indonesia</title>
<author><name sortKey="Baker, Stephen" sort="Baker, Stephen" uniqKey="Baker S" first="Stephen" last="Baker">Stephen Baker</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>The Wellcome Trust Sanger Institute</s1>
<s2>Hinxton, Cambridgeshire</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<wicri:noRegion>The Wellcome Trust Sanger Institute</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Oxford University Clinical Research Unit</s1>
<s2>Ho Chi Minh City</s2>
<s3>VNM</s3>
<sZ>1 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>Viêt Nam</country>
<wicri:noRegion>Oxford University Clinical Research Unit</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Holt, Kathryn" sort="Holt, Kathryn" uniqKey="Holt K" first="Kathryn" last="Holt">Kathryn Holt</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>The Wellcome Trust Sanger Institute</s1>
<s2>Hinxton, Cambridgeshire</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<wicri:noRegion>The Wellcome Trust Sanger Institute</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Van De Vosse, Esther" sort="Van De Vosse, Esther" uniqKey="Van De Vosse E" first="Esther" last="Van De Vosse">Esther Van De Vosse</name>
<affiliation wicri:level="3"><inist:fA14 i1="03"><s1>Department of Infectious Diseases, Leiden University Medical Centre</s1>
<s2>Leiden</s2>
<s3>NLD</s3>
<sZ>3 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>Pays-Bas</country>
<placeName><settlement type="city">Leyde</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Roumagnac, Philippe" sort="Roumagnac, Philippe" uniqKey="Roumagnac P" first="Philippe" last="Roumagnac">Philippe Roumagnac</name>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Centre National de la Recherche Scientifique</s1>
<s2>Saint Paul Lez Durance</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>Saint Paul Lez Durance</wicri:noRegion>
<wicri:noRegion>Centre National de la Recherche Scientifique</wicri:noRegion>
<wicri:noRegion>Centre National de la Recherche Scientifique</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Whitehead, Sally" sort="Whitehead, Sally" uniqKey="Whitehead S" first="Sally" last="Whitehead">Sally Whitehead</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>The Wellcome Trust Sanger Institute</s1>
<s2>Hinxton, Cambridgeshire</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<wicri:noRegion>The Wellcome Trust Sanger Institute</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="King, Emma" sort="King, Emma" uniqKey="King E" first="Emma" last="King">Emma King</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>The Wellcome Trust Sanger Institute</s1>
<s2>Hinxton, Cambridgeshire</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<wicri:noRegion>The Wellcome Trust Sanger Institute</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ewels, Philip" sort="Ewels, Philip" uniqKey="Ewels P" first="Philip" last="Ewels">Philip Ewels</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>The Wellcome Trust Sanger Institute</s1>
<s2>Hinxton, Cambridgeshire</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<wicri:noRegion>The Wellcome Trust Sanger Institute</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Keniry, Andrew" sort="Keniry, Andrew" uniqKey="Keniry A" first="Andrew" last="Keniry">Andrew Keniry</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>The Wellcome Trust Sanger Institute</s1>
<s2>Hinxton, Cambridgeshire</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<wicri:noRegion>The Wellcome Trust Sanger Institute</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Weill, Francois Xavier" sort="Weill, Francois Xavier" uniqKey="Weill F" first="Francois-Xavier" last="Weill">Francois-Xavier Weill</name>
<affiliation wicri:level="3"><inist:fA14 i1="05"><s1>Centre National de Référence des Salmonella, Institut Pasteur</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lightfoot, Diane" sort="Lightfoot, Diane" uniqKey="Lightfoot D" first="Diane" last="Lightfoot">Diane Lightfoot</name>
<affiliation wicri:level="4"><inist:fA14 i1="06"><s1>Microbiological Diagnostic Unit-Public Health Laboratory, University of Melbourne</s1>
<s2>Melbourne, Vtctoria</s2>
<s3>AUS</s3>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<placeName><settlement type="city">Melbourne</settlement>
<region type="état">Victoria (État)</region>
</placeName>
<orgName type="university">Université de Melbourne</orgName>
</affiliation>
</author>
<author><name sortKey="Van Dissel, Jaap T" sort="Van Dissel, Jaap T" uniqKey="Van Dissel J" first="Jaap T." last="Van Dissel">Jaap T. Van Dissel</name>
<affiliation wicri:level="3"><inist:fA14 i1="03"><s1>Department of Infectious Diseases, Leiden University Medical Centre</s1>
<s2>Leiden</s2>
<s3>NLD</s3>
<sZ>3 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>Pays-Bas</country>
<placeName><settlement type="city">Leyde</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Sanderson, Kenneth E" sort="Sanderson, Kenneth E" uniqKey="Sanderson K" first="Kenneth E." last="Sanderson">Kenneth E. Sanderson</name>
<affiliation wicri:level="4"><inist:fA14 i1="07"><s1>Department of Biological Sciences, University of Calgary</s1>
<s2>Calgary, Alberta</s2>
<s3>CAN</s3>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<placeName><settlement type="city">Calgary</settlement>
<region type="state">Alberta</region>
</placeName>
<orgName type="university">Université de Calgary</orgName>
</affiliation>
</author>
<author><name sortKey="Farrar, Jeremy" sort="Farrar, Jeremy" uniqKey="Farrar J" first="Jeremy" last="Farrar">Jeremy Farrar</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Oxford University Clinical Research Unit</s1>
<s2>Ho Chi Minh City</s2>
<s3>VNM</s3>
<sZ>1 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>Viêt Nam</country>
<wicri:noRegion>Oxford University Clinical Research Unit</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Achtman, Mark" sort="Achtman, Mark" uniqKey="Achtman M" first="Mark" last="Achtman">Mark Achtman</name>
<affiliation wicri:level="1"><inist:fA14 i1="08"><s1>Environmental Research Institute, University College Cork</s1>
<s2>Cork</s2>
<s3>IRL</s3>
<sZ>14 aut.</sZ>
</inist:fA14>
<country>Irlande (pays)</country>
<wicri:noRegion>Cork</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Deloukas, Panagiotis" sort="Deloukas, Panagiotis" uniqKey="Deloukas P" first="Panagiotis" last="Deloukas">Panagiotis Deloukas</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>The Wellcome Trust Sanger Institute</s1>
<s2>Hinxton, Cambridgeshire</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<wicri:noRegion>The Wellcome Trust Sanger Institute</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Dougan, Gordon" sort="Dougan, Gordon" uniqKey="Dougan G" first="Gordon" last="Dougan">Gordon Dougan</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>The Wellcome Trust Sanger Institute</s1>
<s2>Hinxton, Cambridgeshire</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<wicri:noRegion>The Wellcome Trust Sanger Institute</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">08-0251112</idno>
<date when="2008">2008</date>
<idno type="stanalyst">PASCAL 08-0251112 INIST</idno>
<idno type="RBID">Pascal:08-0251112</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">003584</idno>
<idno type="wicri:Area/PascalFrancis/Curation">002A63</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">003188</idno>
<idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">003188</idno>
<idno type="wicri:doubleKey">0095-1137:2008:Baker S:high:throughput:genotyping</idno>
<idno type="wicri:Area/Main/Merge">009602</idno>
<idno type="wicri:source">PMC</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395080</idno>
<idno type="RBID">PMC:2395080</idno>
<idno type="wicri:Area/Pmc/Corpus">001010</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001010</idno>
<idno type="wicri:Area/Pmc/Curation">000E71</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000E71</idno>
<idno type="wicri:Area/Pmc/Checkpoint">002993</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">002993</idno>
<idno type="wicri:Area/Ncbi/Merge">000352</idno>
<idno type="wicri:Area/Ncbi/Curation">000352</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000352</idno>
<idno type="wicri:doubleKey">0095-1137:2008:Baker S:high:throughput:genotyping</idno>
<idno type="wicri:Area/Main/Merge">008E38</idno>
<idno type="wicri:Area/Main/Curation">008C92</idno>
<idno type="wicri:Area/Main/Exploration">008C92</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">High-Throughput Genotyping of Salmonella enterica Serovar Typhi Allowing Geographical Assignment of Haplotypes and Pathotypes within an Urban District of Jakarta, Indonesia</title>
<author><name sortKey="Baker, Stephen" sort="Baker, Stephen" uniqKey="Baker S" first="Stephen" last="Baker">Stephen Baker</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>The Wellcome Trust Sanger Institute</s1>
<s2>Hinxton, Cambridgeshire</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<wicri:noRegion>The Wellcome Trust Sanger Institute</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Oxford University Clinical Research Unit</s1>
<s2>Ho Chi Minh City</s2>
<s3>VNM</s3>
<sZ>1 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>Viêt Nam</country>
<wicri:noRegion>Oxford University Clinical Research Unit</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Holt, Kathryn" sort="Holt, Kathryn" uniqKey="Holt K" first="Kathryn" last="Holt">Kathryn Holt</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>The Wellcome Trust Sanger Institute</s1>
<s2>Hinxton, Cambridgeshire</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<wicri:noRegion>The Wellcome Trust Sanger Institute</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Van De Vosse, Esther" sort="Van De Vosse, Esther" uniqKey="Van De Vosse E" first="Esther" last="Van De Vosse">Esther Van De Vosse</name>
<affiliation wicri:level="3"><inist:fA14 i1="03"><s1>Department of Infectious Diseases, Leiden University Medical Centre</s1>
<s2>Leiden</s2>
<s3>NLD</s3>
<sZ>3 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>Pays-Bas</country>
<placeName><settlement type="city">Leyde</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Roumagnac, Philippe" sort="Roumagnac, Philippe" uniqKey="Roumagnac P" first="Philippe" last="Roumagnac">Philippe Roumagnac</name>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Centre National de la Recherche Scientifique</s1>
<s2>Saint Paul Lez Durance</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>Saint Paul Lez Durance</wicri:noRegion>
<wicri:noRegion>Centre National de la Recherche Scientifique</wicri:noRegion>
<wicri:noRegion>Centre National de la Recherche Scientifique</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Whitehead, Sally" sort="Whitehead, Sally" uniqKey="Whitehead S" first="Sally" last="Whitehead">Sally Whitehead</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>The Wellcome Trust Sanger Institute</s1>
<s2>Hinxton, Cambridgeshire</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<wicri:noRegion>The Wellcome Trust Sanger Institute</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="King, Emma" sort="King, Emma" uniqKey="King E" first="Emma" last="King">Emma King</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>The Wellcome Trust Sanger Institute</s1>
<s2>Hinxton, Cambridgeshire</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<wicri:noRegion>The Wellcome Trust Sanger Institute</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ewels, Philip" sort="Ewels, Philip" uniqKey="Ewels P" first="Philip" last="Ewels">Philip Ewels</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>The Wellcome Trust Sanger Institute</s1>
<s2>Hinxton, Cambridgeshire</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<wicri:noRegion>The Wellcome Trust Sanger Institute</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Keniry, Andrew" sort="Keniry, Andrew" uniqKey="Keniry A" first="Andrew" last="Keniry">Andrew Keniry</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>The Wellcome Trust Sanger Institute</s1>
<s2>Hinxton, Cambridgeshire</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<wicri:noRegion>The Wellcome Trust Sanger Institute</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Weill, Francois Xavier" sort="Weill, Francois Xavier" uniqKey="Weill F" first="Francois-Xavier" last="Weill">Francois-Xavier Weill</name>
<affiliation wicri:level="3"><inist:fA14 i1="05"><s1>Centre National de Référence des Salmonella, Institut Pasteur</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lightfoot, Diane" sort="Lightfoot, Diane" uniqKey="Lightfoot D" first="Diane" last="Lightfoot">Diane Lightfoot</name>
<affiliation wicri:level="4"><inist:fA14 i1="06"><s1>Microbiological Diagnostic Unit-Public Health Laboratory, University of Melbourne</s1>
<s2>Melbourne, Vtctoria</s2>
<s3>AUS</s3>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<placeName><settlement type="city">Melbourne</settlement>
<region type="état">Victoria (État)</region>
</placeName>
<orgName type="university">Université de Melbourne</orgName>
</affiliation>
</author>
<author><name sortKey="Van Dissel, Jaap T" sort="Van Dissel, Jaap T" uniqKey="Van Dissel J" first="Jaap T." last="Van Dissel">Jaap T. Van Dissel</name>
<affiliation wicri:level="3"><inist:fA14 i1="03"><s1>Department of Infectious Diseases, Leiden University Medical Centre</s1>
<s2>Leiden</s2>
<s3>NLD</s3>
<sZ>3 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>Pays-Bas</country>
<placeName><settlement type="city">Leyde</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Sanderson, Kenneth E" sort="Sanderson, Kenneth E" uniqKey="Sanderson K" first="Kenneth E." last="Sanderson">Kenneth E. Sanderson</name>
<affiliation wicri:level="4"><inist:fA14 i1="07"><s1>Department of Biological Sciences, University of Calgary</s1>
<s2>Calgary, Alberta</s2>
<s3>CAN</s3>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<placeName><settlement type="city">Calgary</settlement>
<region type="state">Alberta</region>
</placeName>
<orgName type="university">Université de Calgary</orgName>
</affiliation>
</author>
<author><name sortKey="Farrar, Jeremy" sort="Farrar, Jeremy" uniqKey="Farrar J" first="Jeremy" last="Farrar">Jeremy Farrar</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Oxford University Clinical Research Unit</s1>
<s2>Ho Chi Minh City</s2>
<s3>VNM</s3>
<sZ>1 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>Viêt Nam</country>
<wicri:noRegion>Oxford University Clinical Research Unit</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Achtman, Mark" sort="Achtman, Mark" uniqKey="Achtman M" first="Mark" last="Achtman">Mark Achtman</name>
<affiliation wicri:level="1"><inist:fA14 i1="08"><s1>Environmental Research Institute, University College Cork</s1>
<s2>Cork</s2>
<s3>IRL</s3>
<sZ>14 aut.</sZ>
</inist:fA14>
<country>Irlande (pays)</country>
<wicri:noRegion>Cork</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Deloukas, Panagiotis" sort="Deloukas, Panagiotis" uniqKey="Deloukas P" first="Panagiotis" last="Deloukas">Panagiotis Deloukas</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>The Wellcome Trust Sanger Institute</s1>
<s2>Hinxton, Cambridgeshire</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<wicri:noRegion>The Wellcome Trust Sanger Institute</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Dougan, Gordon" sort="Dougan, Gordon" uniqKey="Dougan G" first="Gordon" last="Dougan">Gordon Dougan</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>The Wellcome Trust Sanger Institute</s1>
<s2>Hinxton, Cambridgeshire</s2>
<s3>GBR</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<wicri:noRegion>The Wellcome Trust Sanger Institute</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Journal of clinical microbiology : (Print)</title>
<title level="j" type="abbreviated">J. clin. microbiol. : (Print)</title>
<idno type="ISSN">0095-1137</idno>
<imprint><date when="2008">2008</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Journal of clinical microbiology : (Print)</title>
<title level="j" type="abbreviated">J. clin. microbiol. : (Print)</title>
<idno type="ISSN">0095-1137</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Genotype</term>
<term>Haplotype</term>
<term>High throughput screening</term>
<term>Indonesia</term>
<term>Microbiology</term>
<term>Pathotype</term>
<term>Salmonella typhi</term>
<term>Typing</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Salmonella typhi</term>
<term>Criblage haut débit</term>
<term>Génotype</term>
<term>Typage</term>
<term>Haplotype</term>
<term>Pathotype</term>
<term>Indonésie</term>
<term>Microbiologie</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Indonésie</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">High-throughput epidemiological typing systems that provide phylogenetic and genotypic information are beneficial for tracking bacterial pathogens in the field. The incidence of Salmonella enterica serovar Typhi infection in Indonesia is high and is associated with atypical phenotypic traits such as expression of the j and the z66 flagellum antigens. Utilizing a high-throughput genotyping platform to investigate known nucleotide polymorphisms dispersed around the genome, we determined the haplotypes of 140 serovar Typhi isolates associated with Indonesia. We identified nine distinct serovar Typhi haplotypes circulating in Indonesia for more than 30 years, with eight of these present in a single Jakarta suburb within a 2-year period. One dominant haplotype, H59, is associated with j and z66 flagellum expression, representing a potential pathotype unique to Indonesia. Phylogenetic analysis suggests that H59 z66<sup>+</sup>
,j<sup>+</sup>
 isolates emerged relatively recently in terms of the origin of serovar Typhi and are geographically restricted. These data demonstrate the potential of high-throughput genotyping platforms for analyzing serovar Typhi populations in the field. The study also provides insight into the evolution of serovar Typhi and demonstrates the value of a molecular epidemiological technique that is exchangeable, that is internet friendly, and that has global utility.</div>
</front>
</TEI>
<affiliations><list><country><li>Australie</li>
<li>Canada</li>
<li>France</li>
<li>Irlande (pays)</li>
<li>Pays-Bas</li>
<li>Royaume-Uni</li>
<li>Viêt Nam</li>
</country>
<region><li>Alberta</li>
<li>Hollande-Méridionale</li>
<li>Victoria (État)</li>
<li>Île-de-France</li>
</region>
<settlement><li>Calgary</li>
<li>Leyde</li>
<li>Melbourne</li>
<li>Paris</li>
</settlement>
<orgName><li>Université de Calgary</li>
<li>Université de Melbourne</li>
</orgName>
</list>
<tree><country name="Royaume-Uni"><noRegion><name sortKey="Baker, Stephen" sort="Baker, Stephen" uniqKey="Baker S" first="Stephen" last="Baker">Stephen Baker</name>
</noRegion>
<name sortKey="Deloukas, Panagiotis" sort="Deloukas, Panagiotis" uniqKey="Deloukas P" first="Panagiotis" last="Deloukas">Panagiotis Deloukas</name>
<name sortKey="Dougan, Gordon" sort="Dougan, Gordon" uniqKey="Dougan G" first="Gordon" last="Dougan">Gordon Dougan</name>
<name sortKey="Ewels, Philip" sort="Ewels, Philip" uniqKey="Ewels P" first="Philip" last="Ewels">Philip Ewels</name>
<name sortKey="Holt, Kathryn" sort="Holt, Kathryn" uniqKey="Holt K" first="Kathryn" last="Holt">Kathryn Holt</name>
<name sortKey="Keniry, Andrew" sort="Keniry, Andrew" uniqKey="Keniry A" first="Andrew" last="Keniry">Andrew Keniry</name>
<name sortKey="King, Emma" sort="King, Emma" uniqKey="King E" first="Emma" last="King">Emma King</name>
<name sortKey="Whitehead, Sally" sort="Whitehead, Sally" uniqKey="Whitehead S" first="Sally" last="Whitehead">Sally Whitehead</name>
</country>
<country name="Viêt Nam"><noRegion><name sortKey="Baker, Stephen" sort="Baker, Stephen" uniqKey="Baker S" first="Stephen" last="Baker">Stephen Baker</name>
</noRegion>
<name sortKey="Farrar, Jeremy" sort="Farrar, Jeremy" uniqKey="Farrar J" first="Jeremy" last="Farrar">Jeremy Farrar</name>
</country>
<country name="Pays-Bas"><region name="Hollande-Méridionale"><name sortKey="Van De Vosse, Esther" sort="Van De Vosse, Esther" uniqKey="Van De Vosse E" first="Esther" last="Van De Vosse">Esther Van De Vosse</name>
</region>
<name sortKey="Van Dissel, Jaap T" sort="Van Dissel, Jaap T" uniqKey="Van Dissel J" first="Jaap T." last="Van Dissel">Jaap T. Van Dissel</name>
</country>
<country name="France"><noRegion><name sortKey="Roumagnac, Philippe" sort="Roumagnac, Philippe" uniqKey="Roumagnac P" first="Philippe" last="Roumagnac">Philippe Roumagnac</name>
</noRegion>
<name sortKey="Weill, Francois Xavier" sort="Weill, Francois Xavier" uniqKey="Weill F" first="Francois-Xavier" last="Weill">Francois-Xavier Weill</name>
</country>
<country name="Australie"><region name="Victoria (État)"><name sortKey="Lightfoot, Diane" sort="Lightfoot, Diane" uniqKey="Lightfoot D" first="Diane" last="Lightfoot">Diane Lightfoot</name>
</region>
</country>
<country name="Canada"><region name="Alberta"><name sortKey="Sanderson, Kenneth E" sort="Sanderson, Kenneth E" uniqKey="Sanderson K" first="Kenneth E." last="Sanderson">Kenneth E. Sanderson</name>
</region>
</country>
<country name="Irlande (pays)"><noRegion><name sortKey="Achtman, Mark" sort="Achtman, Mark" uniqKey="Achtman M" first="Mark" last="Achtman">Mark Achtman</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 008C92 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 008C92 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Asie
   |area=    AustralieFrV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     Pascal:08-0251112
   |texte=   High-Throughput Genotyping of Salmonella enterica Serovar Typhi Allowing Geographical Assignment of Haplotypes and Pathotypes within an Urban District of Jakarta, Indonesia
}}

This area was generated with Dilib version V0.6.33.
Data generation: Tue Dec 5 10:43:12 2017. Site generation: Tue Mar 5 14:07:20 2024

Serveur d'exploration sur les relations entre la France et l'Australie

High-Throughput Genotyping of Salmonella enterica Serovar Typhi Allowing Geographical Assignment of Haplotypes and Pathotypes within an Urban District of Jakarta, Indonesia

High-Throughput Genotyping of Salmonella enterica Serovar Typhi Allowing Geographical Assignment of Haplotypes and Pathotypes within an Urban District of Jakarta, Indonesia

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Serveur d'exploration sur les relations entre la France et l'Australie
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.